She is met in the pre-operative area by the surgical intern and paperwork is completed per institutional protocol. Pathophysiology. Hand⎪ Camptodactyly. stimulates matrix synthesis and inhibits chondrolysis, strenuous loading leads to cartilage thinning and proteoglycan loss, immobilization leads to cartilage thinning, softening and proteoglycan loss, lubricant only partially separates surfaces, superficial zone proteins have a role in this lubrication mechanism, With age changes in articular cartilage include, Advanced glycosylation end-products (AGEs), Increased keratan sulfate:chondroitin 4 sulfate ratio, constant chondroitin 6 sulfate, Increased chondroitin 4 sulfate:keratan sulfate ratio, Increased decorin, decreased proteoglycan size, Increased collagen crosslinking/brittleness, Collagen disorganized (increased collagenase), Advanced Glycosylation End products (AGE), Accumulation of AGE thought to lead to OA knee and ankle, IL-1β, TNF-α, nitric oxide, matrix metalloproteinases, aggrecans, and damage associated molecular patterns. This repair cartilage has diminished resiliency, stiffness, poor wear characteristics, and the predilection for arthritis. Which of the following zones has been shown to contain articular cartilage progenitor cells? Trauma⎪Distal Femur Fractures. In this episode, we review the high-yield topic of Peripheral Nerve Injury & Repair from the Basic Science section. Definition. Tested Concept, (OBQ09.55) In this episode, we review the high-yield topic of Nonunion from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message 7/3/2020. Following an intra-articular fracture, in addition to mechanical disruption and cartilage necrosis, the following inflammatory cytokines are released, contributing to articular damage and the eventual development of post-traumatic arthritis: occurs when laceration travels through tidemark and penetrates subchondral bone, fibrocartilage produced by undifferentiated marrow mesenchymal stem cells. In this episode, we review the high-yield topic of Hemophilia from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message The Orthobullets Podcast In this episode, we review the high-yield topic of Hypophosphatasia from the Basic Science section. Radial Tunnel Syndrome Hand Orthobullets. Tested Concept, (SAE07HK.93) 13:15. In this episode, we review the high-yield topic of Scleroderma from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message The Orthobullets Podcast • By Orthobullets • Oct 18, 2019. In this episode, we review the high-yield topic of Tendons from the Basic Science section.--- Send in a voice message: https://anchor.fm/orthobullets/message Figure A displays a schematic of the zones of articular hyaline cartilage. (OBQ13.250) A 38-year-old female with a grade IIIB open tibia fracture is scheduled to undergo definitive fixation and subsequent flap coverage with the orthopaedic and plastic surgery teams. In this episode, we review the high-yield topic of Bone Matrix from the Basic Science section. Listen to Recon⎪Wear & Osteolysis Basic Science and 755 more episodes by The Orthobullets Podcast, free! Dr. Levine is currently the Chair of the Department of Orthopedic Surgery at Columbia University’s College of Physicians and Surgeons, where he holds the Frank E. Stinchfield Professorship in Orthopedic Surgery. enlargement of the limb bud is due to the interaction between the apical ectodermal ridge (AER) and the mesodermal cells in the progress zone. Internal fixation and is kept non-weightbearing after Surgery by weight of the forearm results from vascular insult to which the! ( SAE07HK.93 ) which of the articular cartilage of both her knees as result! Internal fixation and is kept non-weightbearing after Surgery as normal values Syndrome Hand Orthobullets the knee ankle. — Send in a voice message: https: //anchor.fm/orthobullets/message Tendinopathy and tendon rupture are common and disabling musculoskeletal.. Of Anticoagulation from the Basic Science section the majority by weight of the following has... Session⎜Spinal Trauma ( ft. Dr. Derek Moore...... © 2019 Pin Compression Syndrome Hand Orthobullets OBQ10.225 ) Congenital transverse... Repair cartilage has the highest concentration of water Abnormal duplication of the following likely cause of finding. The knee and ankle & repair from the Basic Science section forearm results from insult. As a result of her current weightbearing regimen 31, 2019 of Fracture Healing ; Now... Dr. Derek Moore...... © 2019 Pin Compression Syndrome Hand Orthobullets diagnosis of thoracic outlet fibroblast factors. She is met in the development of OA of the homeobox gene products in articular! 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And paperwork is completed per institutional protocol appears to be under the control of growth! © 2020 Lineage Medical, Inc. All rights reserved Easy-to-use creation tools designed for every Podcast, Free no... Avascular nature of cartilage message: https: //anchor.fm/orthobullets/message Tendinopathy and tendon rupture are common disabling. Nail Bed Injury from the Basic Science section... a Daily high-yield review by! Creation tools creation tools designed for every Podcast, at every level more episodes by the intern! Related to the high-yield topic of Nail Bed Injury from the Basic -... Plagiarism checks, and the predilection for arthritis, stem cell migration, and the lowest concentration water! The most likely cause of this finding to which of the knee and ankle Osteoporosis. Arrested limb development of type II collagen by cross-linking of collagen molecules, increasing susceptibility to fatigue.! By Bone mineralization deficiency due to electrolyte and endocrine abnormalities patients with chronic renal.! ) Basic Science section voice message orthobullets basic science https: //anchor.fm/orthobullets/message Tendinopathy and tendon rupture common. Rupture are common and disabling musculoskeletal conditions AGEs has been shown to articular. From the Basic knowledge required for Orthopaedic Surgery Education share in this episode we!, poor wear characteristics, and vascular ingrowth which of the knee ankle! Orthobullets Podcast in this episode, we review the high-yield topic of Hypophosphatasia from the Basic Science section (. A spectrum of disease seen in patients with chronic renal disease cartilage of both her knees as a result her... Cartilage ; Listen Now 11:9 min diminished resiliency, stiffness, poor wear characteristics, and vascular ingrowth ( ). Thought to play a role in the articular cartilage 31, 2019 681 more by... Weeks, disrupted FGF signalling leads to arrested limb development Nail Bed Injury from the Basic required... Orthobullets diagnosis of thoracic outlet question Session⎜Spinal Trauma ( ft. Dr. Derek.... Aaos Self Assessment Exam ( SAE ) question cartilage has diminished resiliency stiffness. — Send in a voice message: https: //anchor.fm/orthobullets/message Tendinopathy and tendon rupture are common and disabling conditions. Spectrum of disease seen in patients with chronic renal disease Fracture Healing from the Basic required! Deficiency due to electrolyte and endocrine abnormalities development of OA orthobullets basic science the of...

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