Herbion Naturals Ivy Leaf Cough Syrup with Thyme and Licorice, 5 … 13 children belonged to the class group 6–11 years with an average height of 136.0 cm and an average weight of 32.3 kg. NAC is used as a treatment option in various conditions in which there are problems with clearance of lung mucosal secretions. IVY leaf. Material and Methods. There's a problem loading this menu right now. It is the most common disease in industrialized countries, and thus herbal expectorants enjoy a high popularity in many European countries due to their favorable risk-benefit ratio. These positive results for the herbal medication correspond to the pharmacological actions of ivy. Sydler Remedies Private Limited - Category: Pharma & Supplements. The first patient was recruited in January 2017, and the last visit of the last patient was in March 2018. L. Ivy leaf preparations are obtained as dry, liquid and soft extracts by putting the plant material in a solvent (such as ethanol) to dissolve compounds and form a liquid extract. Introduction: Ivy leaf extract is an essential oil extracted from plant leaves. Essentially, all captured data are calculated as frequency distributions and descriptive analysis (e.g., averages, medians, standard deviations, minimums, and maximums). Our cough syrup works as a bronchodilator and an expectorant which eases chest congestion, inflammation of the trachea and soothes sore throat. Further, the use of these agents is not recommended as a general practice according to present guidelines [21]. Active ingredient: Each 5 ml of syrup contains 35 mg of extract (as dry extract) from ivy leaf (Hedera helix L.) (5 - 7.5 : 1). These components are supportive of healthy mucous membranes and defend against occasional irritation of the lung and bronchial passages. Further, the severity of the disease was rated by a 7-stage-score and coughing quality (auscultation) by a 3-stage-score. An interim analysis, which was performed 15 months after study start, showed that data of the collected 139 patients were sufficient for an explorative analysis with the group comparison. At the inclusion visit, demographic and anamnestic data as well as the indication and typical complaints were recorded in the case report form. Product: Cofif Syrup. Ivy Leaf Cough Syrup With Thyme & Stevia - Herbion Naturals Relevant concomitant diseases and treatments. Furthermore, concomitant diseases were treated with different antibiotics or other treatment which also might have an impact on the treatment outcome for the acute bronchitis. Alternative & Herbal Products. The authors declare that there are no conflicts of interest. This leads to relaxation in the bronchial muscles and plausibly explains the bronchospasmolytic effect of ivy [24]. Physicians judged the tolerability as “very good” and “good” with 99.1% for the EA 575® group and 95.2% for the ACC group. The average age was 44.3 years for the EA 575® group and 49.1 years for the ACC group. Two galenical formulations of an ivy herbal extract, syrup and cough drops, were tested for their efficacy and safety in the paediatric treatment of cough and bronchitis in two independent open, non‐interventional studies with identical design. However, there are other pharmacologic treatments for impaired mucous secretion clearance including agents such as isotonic saline and acetylcysteine (also known as N-acetylcysteine (NAC)). Maty's Organic Mucus Cough Syrup, Made with Organic Honey, Thyme & Ginger - 6 fl oz. In the current study design (noninterventional study), the physicians were totally free in their prescription decision. Husten und Auswurf: ursachen und Differentialdiagnosen,”, J. E. DeLozier and R. O. Gagnon, “National ambulatory medical care survey: 1989 summary,”, K. F. Chung and I. D. Pavord, “Prevalence, pathogenesis, and causes of chronic cough,”, C. C. S. Lang and T. Wegener, “Efeu in der pädiatrischen Praxis,”, A. Schaefer, F. Ludwig, B. M. Giannetti, M. Bulitta, and A. Wacker, “Efficacy of two dosing schemes of a liquid containing ivy leaves dry extract EA 575 versus placebo in the treatment of acute bronchitis in adults,”, A. Schaefer, M. S. Kehr, B. M. Giannetti, M. Bulitta, and C. Staiger, “A randomized, controlled, double-blind, multi-center trial to evaluate the efficacy and safety of a liquid containing ivy leaves dry extract (EA 575((R))) vs. placebo in the treatment of adults with acute cough,”, P. Kardos, Q. Dinh, K.-H. Fuchs et al., “Leitlinie der deutschen gesellschaft für pneumologie und beatmungsmedizin zur diagnostik und therapie von erwachsenen patienten mit husten,”, P. Kardos, S. Lehrl, W. Kamin, and H. Matthys, “Assessment of the effect of pharmacotherapy in common cold/acute bronchitis - the bronchitis severity scale (BSS),”, B. Kemmerich, R. Eberhardt, and H. Stammer, “Efficacy and tolerability of a fluid extract combination of thyme herb and ivy leaves and matched placebo in adults suffering from acute bronchitis with productive cough,”, F. J. Martinez, “Acute bronchitis: state of the art diagnosis and therapy,”, A. Gillissen, C. Gessner, S. Hammerschmidt, G. Hoheisel, and H. Wirtz, “Acute bronchitis: when are antibiotics, and when is symptomatic treatment indicated?”, G. Höffken, J. Lorenz, W. Kern et al., “S3-guideline on ambulant acquired pneumonia and deep airway infections,”, N. A. Sathe, S. Krishnaswami, J. Andrews, C. Ficzere, and M. L. McPheeters, “Pharmacologic agents that promote airway clearance in hospitalized subjects: a systematic review,”, Y. Bolbot, E. Prokhorov, S. Mokia, and A. Yurtseva, “Comparing the efficacy and safety of high-concentrate (5-7.5:1) ivy leaves extract and acetylcysteine for treatment of children with acute bronchitis,”, A. Sieben, L. Prenner, T. Sorkalla et al., “Alpha-hederin, but not hederacoside C and hederagenin from Hedera helix, affects the binding behavior, dynamics, and regulation of beta 2-adrenergic receptors,”. It is characterized by a persistent cough which can be productive or dry. The average duration for symptoms at entry visit was 2.341 days in the EA 575® group and 2.33 days in the ACC group. Zarbee's Naturals Children's All in One Nighttime Cough Syrup + Mucus, Throat & Nasal, Natural Grape Flavor, 4 Ounce, Prospan Cough Syrup - 100ml CHESTY Cough Relief & Mucus Relief. The study was conducted at 25 medical practices throughout Switzerland as prospective, open, noninterventional study. Observations of the tolerability were comparable for both products. Extraction solvent: ethanol 30 % w/w. Totally, 25 physicians were recruited in Switzerland who participated with 139 patients. https://www.blackmores.com.au/.../ivy-leaf-for-cough-relief Symptoms could last up to 3 days and not longer to assure the acute situation. We start with our proprietary Dark Honey Blend and add English Ivy Leaf extract and Marshmallow Root Extract to soothe irritated throats and help your child clear mucus when they are coughing. containing ivy leaf extract. Other secondary parameters from patients’ assessment coming from the diary included the coughing intensity, chest pain during coughing, dyspnoea during coughing, cough-related sleep disturbances, and possibility to cough-up mucus resulting in a comparable improvement. The present Swiss study investigated the intake of EA 575® and acetylcysteine and confirmed the results from Lang et al. The validated method was successfully applied to quantify all six compounds in a 30% ethanol ivy leaf extract and 13 ivy leaf extract products. 47 male and 71 female subjects were included into the EA 575® group, and 11 male and 10 female subjects were included into the ACC group. Cough and fever are the most common symptoms of acute bronchitis in children. These effects are attributable, in particular, to the therapeutically important constituents of the ivy leaf extract, which belong to the class of triterpene saponins such as hederacoside C (Figure 1), a marker and an active ingredient of ivy leaf extract [7–10]. There were 4 different consent forms used in the study depending on the age of the subjects: one consent form for adult subjects, one form for subjects ranging between 14 and 18 years old (signed by the subjects), one form for subjects between ages 11 and 13 years who can already read the document by themselves (signed by the parents), and one form for parents of subjects between 6 and 11 years (signed by parents). In the ACC group, 21 × 7.48 = 157 patient days were calculated together across all dosage forms. At the beginning, BSS average was 6.5 points in the EA 575® group and 6.7 points in the group of ACC patients, respectively, showing a moderate impairment for both. Effect or tolerability data was compared by repeated general linear model analysis using data from entry and final visits as intrasubject variables, treatment as between subject factor, and sex and child/adults as covariates. $16.39$16.39 ($3.21/Fl Oz) FREE Shipping. At entry visit, duration of symptoms was assessed as well (Table 3). There was a significant improvement in the reduction of both groups from baseline to end visit. dried ivy leaf extract 【Botanic Name】Hedera helix L. 【Use Part】Leaf 【Specifications】10%-40% Hederacosides, 3%-20% Hederacoside C, 10:1. For dyspnoea during coughing, better improvement was seen in the EA 575® group. The present noninterventional study was intended to gain further data on the application of a cough syrup containing ivy leaf extract EA 575® by evaluating its efficacy and safety in children and adults with symptoms of acute bronchitis. Bottles), Garden of Life Elderberry Zinc Support for Adults Kids 12 and Older, mykind Organics Cough & Mucus Syrup with Ivy Leaf, Vitamin C Echinacea, No Added Sugars, 6.59 Fl Oz, Garden of Life Elderberry Zinc Immune Support for Kids, mykind Organics Kids Cough & Mucus Immune Syrup with Ivy Leaf, Vitamin C and Echinacea for Children, Alcohol Free, No Added Sugars, 3.92 fl oz, Terry Naturally Bronchial Clear Liquid - 3.4 fl oz - Soothing Lung & Upper Respiratory Function Support Supplement, Non-Drowsy, Non-Jittery - Gluten-Free - 20 Servings, Zarbee's Naturals Children's Cough Syrup* with Dark Honey Daytime & Nighttime, Grape, 4 Ounces (Pack of 2), Banyan Botanicals Bronchial Support – Organic Herbal Syrup for Children & Adults – Soothing & Comforting, Supports a Healthy Respiratory System* – 6oz. Herbion Naturals Ivy Leaf Syrup with Thyme and Licorice, 5 fl oz- Helps Maintain Respiratory and Bro… Herbion Naturals Cough Drops with Ivy Leaf, Thyme & Licorice Extracts – 25 Drops – Herbal Expectorant – Relieves Cough, Sore Throat & Bronchial Irritation – for Adults & Children, Urban Moonshine Clear Chest | Organic Herbal First Aid Supplement with Elecampane & Honey Syrup | Fast-Acting Bronchial Support | 4.2 FL OZ (Pack of 1), Boericke and Tafel Cough and Bronchitis Syrup with Zinc, 4 Fluid Ounce, Zarbee's Naturals Children's Cough Syrup* + Mucus with Dark Honey, Grape Flavor, 4 Ounce Bottle, Zarbee's Child Natural Cough Syrup 3-day Pack Day/night Dk Honey Mucus Relief - 4 oz each (12 oz total), Zarbee's Naturals Baby Immune Support* & Vitamins & Baby Cough Syrup + Mucus, 2 Ounce Bottles (Value Twin Pack), Hedelix Cough Syrup with Ivy Extract 100ml/3.4 Fl Oz, Prospan Cough Syrup - 200ml CHESTY Cough Relief & Mucus Relief, Redd Remedies, Throat & Bronchial Syrup, Natural Cough Suppressant, Zarbee's Naturals Baby Soothing Chest Rub with Eucalyptus, Lavender & Beeswax, 1.5 Ounce, Mommy's Bliss Organic Kids Cough Syrup + Immune Support Day & Night Combo Pack, Ages 1 Year+ - 8 fl oz, Nature's Way Sambucus HoneyBerry Cough Syrup for Kids, Vegetarian, 4 Fl Oz, Zarbee's Naturals Children's Cough Syrup + Mucus & Immune, Natural Berry Flavor, 4 Ounce, Broncolin Honey Syrup with Plant Extracts to Help Relieve Cough, Dietary Supplement, 11.4 Oz, Bottle, Buckleys Original Cough Congestion Syrup 200 Ml, Herbion Naturals Respiratory Care Granules With Natural Lemon Flavor, 10 count sachet - Help Relieve Cold and Flu Symptoms, Promote Healthy Respiratory Function, Optimize Immune System, Delsym Children's 12 Hr Cough Relief Liquid, Grape, 3 oz (Pack of 2), Natural Relief with Pure & Simple Ingredients. Prospan syrup Ivy leaf dry extract Read all of this leaflet carefully before you start using this medicine because it contains important information for you. 2016-01555). Prospan Chesty Cough Relief - Prospan Australia - Prospan … Coferb Cough Syrup. Herbion Naturals Ivy Leaf Syrup with Thyme and Licorice, 5 fl oz- Helps Maintain Respiratory and Bronchial Health, Supports Healthy Mucous Membranes, Effective for Adults and Children. At entry visit, all clinical assessments including coughing fits, sputum, dyspnoea, rales, severity of the diseases, and coughing quality were rated with moderate intensity in both groups. In addition, the EA 575® preparation showed to be effective in children and adults independent of the indication or concomitant disease and can therefore be used as an alternative to the synthetic ACC preparation. Description: Cofif syrup contains IVY Leaf extract. The tolerability of the herbal medication was very good. In fact, a 2012 study involving 268 children, 0 to 12 years old, discovered that 14 days of treatment with ivy leaf extract (in the form of a cough syrup) was a safe and effective treatment for children with a cough. However, you still need to take ACTIVOX Ivy syrup carefully to get the best results from it. Ivy leaf Extract Syrup. The German College of General Practitioners and Family Physicians (DEGAM) guidance describes the health-economic relevance of acute bronchitis as well [11]. described the mode of action stating that α-hederin inhibited the terbutaline-stimulated internalization of the β2-AR. Demographic parameters were compared between the study groups by chi-squared test or analysis of variance, as appropriate. Another noninterventional study investigated the efficacy and safety of EA 575® in school children with acute bronchitis showing the same improvement in the BSS [12]. ENGELHARD Arzneimittel GmbH & Co. KG Herzbergstraße 3, 61138 Niederdorfelden, Germany Module 1 Common Technical Document Prospan Syrup THR 35693/0001 ivy leaf extract cough offered on the site come in multiple forms such as capsules, powders, and tablets to suit the needs of children and adults alike. Ivy is solid at its base, and then it starts to crawl. At the final visit after seven days of treatment, there was a comparable improvement in both groups for all assessments except dyspnoea and number of cough attacks which showed a higher improvement in the EA 575® group compared with ACC. Two galenical formulations of an ivy herbal extract, syrup and cough drops, were tested for their efficacy and safety in the paediatric treatment of cough and bronchitis in two independent open, non-interventional studies with identical design. The daily self-assessment of patient’s documentation for days 1–6 was done with 5-stage-scored questions except for number of coughing fits and frequency of wake ups at night which have a 4-stage-score. The solvent is then partially or completely evaporated to obtain a soft or dry extract. Hecker M. Efficacy and tolerance of Ivy extract (Prospan®) in patients suffering from respiratory tract diseases. During the final visit, after approximately 1 week, information on the therapy and the course of the symptoms was documented. Within the 139 included patients, only 21 patients were prescribed an acetylcysteine preparation resulting in an unequal group distribution. Viral infection-caused acute bronchitis was the most common disease at entry visit with 53.4% in the EA 575® group and 57.1% in the ACC group, followed by other acute inflammation of the respiratory diseases with 25.4% in the EA 575® group and 33.3% in the ACC group. Average values of physician’s evaluation comparing the final visit with the entry visit. oz. Acute bronchitis affects approximately 5% of adults annually, with a higher incidence observed during winter and fall than in summer and spring [3, 4]. Criteria for exclusion of the documentation were as follows: known hypersensitivity to the active ingredients, treatment with the medications in the last two weeks before study entry, participation in another trial in the same time, and legal incapacity. Probably the drug-related AEs (adverse drug reactions (ADRs)) were in accordance with the known side-effect profile of ivy preparations. Comparable improvement was seen for all symptoms between both groups from the entry to final visit which was statistically significant. Liver disorders. Sieben et al. In the United States, acute bronchitis is the ninth most common illness among outpatients, as reported by physicians [9]. At the end of the treatment, the disease was reduced in both groups to a borderline case of 1.68 points in the EA 575® group and 1.86 points in the ACC group. Ivy leaf is a source of saponins, sterols, flavonoids. Both, physicians and patients described the efficacy of EA 575® comparable with acetylcysteine. Concomitant diseases were mainly treated with antibiotics and other treatment (Table 4). English ivy leaf extract might cause mild stomach problems.. Not enough is known about the safety of applying English ivy to the skin. No statistical significance was seen between the treatments. Subsequently, treatments were prescribed by the doctor. You may need to read it … Out of the 139 data sets, 30 children were analysed with an average height of 136.0 cm and an average weight of 32.3 kg. The study revealed a significant and clinically relevant improvement in patients with acute bronchitis receiving oral treatment with EA 575®. Ivy Leaf Extract. Ivy leaf extract is a traditional ingredient that has been used for centuries to support bronchial health. Other characteristic symptoms include sputum production, shortness of breath, and wheezing related to the obstruction of the inflamed airways. More Buying Choices. 5 Other constituents in the With regard to duration of symptoms, no significant differences were observed between the treatment groups. [12] in children and adults. 22. The severity of the disease started with 4.3 points in the EA 575® group and with 4.24 points in the ACC group showing a moderate status of disease. CZ and EK are the employees of Max Zeller Söhne AG. If the standard deviations of the difference were on average not higher than 2 score points and the alpha error = 0.05, then [17] the nonparametric Mann–Whitney would demonstrate a statistical power (beta error) of more than 90% (GPower, Version 3.1.9, University of Düsseldorf, Germany). There were no specifications available for the calculation of a reasonable sample size; sample size of 300 patients deemed to be sufficient based on the previous studies and practical reasons. * Give Twice Daily Not to exceed 2 servings in 24 hours We are committed to sharing findings related to COVID-19 as quickly as possible. It is an efficient and natural remedy for adult and children. In most cases, only symptomatic treatment is needed [19, 20]. One patient reported diarrhea after she had used EA 575® for two days, and after discontinuing of the medication, the patient had recovered. In principle, antitussives for the treatment of cough as a symptom of an acute bronchitis should have a good tolerability and low toxicity, especially when intended to be used in children. Zarbee's Naturals Cough & Throat Relief + Mucus Nighttime Drink Mix, Apple Spice Flavor, 6 Packets, FREE Shipping on orders over $25 shipped by Amazon, Zarbee's Naturals 99% Honey Cough Soothers, Natural Lemon Flavor, 14 Count, Zarbee's Naturals Baby Cough Syrup* + Mucus, Natural Grape Flavor, 2 Ounces, Integrative Therapeutics - Sambucus - Black Elderberry Syrup - Support Immune System & Cold and Flu Relief Supplement - Berry Flavor - 4 fl oz, Nature's Way Bronchial Soothe Ivy Leaf 99.9% Alcohol-free Non-Drowsy Syrup, 120 ML (4 Fl Oz. The research protocol was reviewed and approved by the Independent Ethics Committee, EKOS (Ethikkommission Ostschweiz) on 16.12.2016 (BASEC Nr. Your recently viewed items and featured recommendations, Select the department you want to search in, All customers get FREE Shipping on orders over $25 shipped by Amazon, Try our simple and soothing honey cough syrup, Zarbee's Naturals Cough Syrup + Mucus Nighttime with Melatonin, Natural Honey Lemon Flavor, 8 Ounce Bottle, Zarbee's Naturals Cough Syrup* + Mucus, Natural Honey Lemon Flavor, 8 Ounce Bottle, Zarbee's Naturals 96% Honey Cough Soothers + Mucus with Ivy Leaf Extract, Lemon Menthol Flavor, 14 Count. The evaluation of the individual data on symptoms was only carried out for those patients in whom the symptom was present at the beginning of the study. 24.6% of the subjects from the EA 575® group suffered from acute bronchitis caused by bacterial infection and 19.0% in the ACC group (Table 2). Furthermore bronchial muscle cells reduce under β2-stimulating conditions the intracellular Ca2+ level. Drop-outs were only those patients, for which no data after intake of the medication were available. Formulations similar to Coferb have been recognized by international clinical trials endorsing safety and efficacy of the product. The physician was totally free in his or her decisions of therapy. The current noninterventional study was performed in 118 patients using EA 575® and 21 patients using ACC for the treatment of acute bronchitis. Ivy has green, shiny and leathery leaves. Coferb contains Ivy Leaf extract that relieves cough and congestion. Complement Med Res 2005;12(6):328-32. The average of findings for coughing fits, sputum, dyspnoea, and rales assessed by the physicians is shown in Figure 1. Product Name: Cofloz Ivy Leaf Cough Syp 120ml Product Form: Syrup Pack Size: 120ml Marketed By: Abbott Laboratories (Pakistan) Ltd Generic Category: Anti-Tussive Ingredients: Ivy Leaf Extract Significant improvement in each of the symptoms from entry visit to final visit (, Assessment of the Efficacy and Safety of Ivy Leaf (, Max Zeller Söhne AG, Seeblickstrasse 4, Romanshorn 8590, Switzerland, CONSULTING HMP, Brückstrasse 11, Weinheim 69469, Germany, Landarztpraxis Sevelen, Velturrietstrasse 5, Sevelen 9475, Switzerland, Evidence-Based Complementary and Alternative Medicine, Acute bronchitis, caused by bacterial infection (ICD-10: J20.0-J20.2) [, Acute bronchitis, caused by viral infection (ICD-10: J20.3-J20.7), Other acute inflammation of the respiratory tract accompanied with cough, The average duration of symptoms at entry visit (days), Concomitant infections and other diseases, None (N; % of patient within treatment group), R. P. Wenzel and A. Syrup: for children up to 12 years, 5 ml, three times daily, and for 12 years and older and adults, 10 ml, three times daily. Product: Cofif Plus Syrup. The present noninterventional study was intended to gain further data on the application of a cough syrup containing ivy leaf extract EA 575® by evaluating its efficacy and safety in children and adults with symptoms of acute bronchitis. Further symptoms are fever and sore throat [1]. Further, the patients were asked to keep a diary during the course of treatment, which includes following symptoms: number of coughing fits during daytime, coughing intensity, chest pain during coughing, dyspnoea during coughing, possibility to cough-up mucus, cough-related sleep disturbances, frequency of wake ups at night, and general well-being. The following symptoms were assessed by the patients or parents (interview by physician): Reduction of coughing intensity, chest pain during coughing, coughing related sleep disturbances, and possibility to cough-up mucus were comparable between both groups. Sign up here as a reviewer to help fast-track new submissions. A previous multicenter study showed that EA 575® exerts mucolytic action equal to acetylcysteine but with better tolerability [23]. The exclusive ivy extract in Bronchial Soothe provides herbal support for optimal lung and bronchial passageway health. Hedera helix preparations (ivy leaf extracts) are worldwide marketed for the treatment of different diseases of the respiratory tract system and include catarrh of the respiratory passages; symptomatic treatment of chronic inflammatory bronchial illnesses; and acute inflammations of the respiratory tract accompanied by coughing (HMPC Assessment) [1]. * Then, we add Turmeric Root for nasal support and Vitamin C and Zinc for immune support. Ivy Leaf Cough Syrup Benefits: Natural formula to reduce coughing, soothe airways and to clear mucus and phlegm or effective congestion and cough relief. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Acetylcysteine (ACC) was chosen as comparator drug (common mono preparations). PROSPANEX® Cough Syrup: 5 ml contains 35 mg Hedera helix leaves dry extract (DER 5–7.5 : 1) as active ingredient, manufactured by Engelhard Arzneimittel GmbH and Co. KG. Each patient had the right to terminate the study participation at any time. 2020, Article ID 1910656, 7 pages, 2020. https://doi.org/10.1155/2020/1910656, 1Max Zeller Söhne AG, Seeblickstrasse 4, Romanshorn 8590, Switzerland, 2CONSULTING HMP, Brückstrasse 11, Weinheim 69469, Germany, 3Landarztpraxis Sevelen, Velturrietstrasse 5, Sevelen 9475, Switzerland. The value of antibiotics or other synthetic products in the treatment of otherwise healthy subjects with acute bronchitis has not been established. Patients themselves rated the following symptoms that were queried by the physician: 5-staged-score for coughing intensity, chest pain during coughing, dyspnoea during coughing, cough-related sleep disturbances, and possibility to cough-up mucus and 4-staged-score for number of coughing fits during daytime. Most of these studies have been performed as uncontrolled, open postmarketing studies, some studies in a randomized placebo-controlled design, and some in a reference-controlled design. The following clinical findings were documented during both visits by the physicians in accordance with the Bronchitis Severity Score (BSS) [16] by a 5-stage assessment: coughing fits, sputum, rales/rhonchi, and dyspnoea during coughing. Hedera helix. It possesses antitussive and expectorant action that provides relief from bronchial cough and other associated respiratory afflictions. Open trials to assess aspects of safety and efficacy of a combined herbal cough syrup with Ivy and Thyme. Diseases with the leading symptom “cough” are economically relevant as respiratory diseases are the most common reason for working incapacity and affect the quality of patient’s life [2]. Esther Kruttschnitt, Tankred Wegener, Catherine Zahner, Silke Henzen-Bücking, "Assessment of the Efficacy and Safety of Ivy Leaf (Hedera helix) Cough Syrup Compared with Acetylcysteine in Adults and Children with Acute Bronchitis", Evidence-Based Complementary and Alternative Medicine, vol. * Soothing syrup provides relief from occasional irritation; Breathe Easy with Bronchial Soothe! EA 575® is effectively independent of the indication or concomitant disease. I was prescribed ivy leaf extract for my (quite heavy) cough. Further, cough-associated sleeping disorders improved more in the EA 575® group. Two-hundred and sixty-eight children aged 0-12 yr were … Before recruitment, the study procedure was explained to the subjects in detail, after which they signed consent forms. Prime members enjoy FREE Delivery and exclusive access to music, movies, TV shows, original audio series, and Kindle books. – Non GMO Sustainably Sourced Vegetarian, Zarbee's Naturals Baby Cough Syrup with Agave & Thyme, Natural Cherry Flavor, 2 Ounce Bottle, Robitussin Naturals Cough Relief & Immune Health Syrup 8.3oz with Honey, Ivy Leaf & Zinc. This results in 118 × 7.48 = 883 patient days. oz. Büechi S, Vögelin R, von Eiff MM, Ramos M, Melzer J. It relieves cough naturally and makes breathing easy. Description. 23. Directions: The clinical effects of Hedera helix have been investigated in a total of more than 20 [12–14] clinical studies mostly in children suffering from upper airway infections. Results of trials with different extracts are only valid for the tested preparation but not for the tested plant [15]. This limitation can be addressed in further interventional studies with an randomized study design. For both treatments, the change from the baseline bronchitis severity score (BSS) to the score at day 7 was calculated. * Ivy leaf supports healthy mucosa beginning with the nose, mouth, and throat, and continuing to the bronchial passageways and lungs. Patients or their parents rated the tolerability as “very good” and “good” with 98.3% in the EA 575® group and 90.5% for the ACC group. ACC mono acetylcysteine preparation (granulate, syrup, or effervescent tablet, products available in the Swiss market): The following doses are recommended according to the summary of product characteristics. ), Clear, Herbion Naturals Ivy Leaf Syrup with Thyme and Licorice, 5 - Helps Maintain Respiratory and Bronchial Health, Supports Healthy Mucous Membranes, Effective for Adults and Children 5 Fl Oz (Pack of 1), Prospan 100mL By Helixia - Ivy Leaf Extract - Relieves Cough, Loosens Mucus & Phlegm, Zarbee's Naturals Baby Cough Syrup + Mucus with Agave & Ivy Leaf, Natural Cherry Flavor, 2 Ounce Bottle, Zarbee's Naturals Children's Cough Syrup* + Mucus Daytime & Nighttime, Grape Flavor, 4 Ounces (Pack of 2), Nature's Way B&T Nighttime Cough & Bronchial Syrup for Restful Sleep Homeopathic, Purple, Cherry 8 Fl Oz, Zarbee's Naturals Children's Cough Syrup* + Mucus with Dark Honey & Ivy Leaf, Cherry Flavor, 4 Ounce Bottle, Helixia Prospan Children's Cough Syrup ages 1 to 11, Children's Robitussin Naturals & Ivy Leaf Cough Relief Gummies, Dietary Supplement, Ages 3+, Honey, 30 Count, Robitussin Naturals Cough Relief Ivy Leaf Gummies 30ct, Robitussin Honey Adult Cough + Chest Congestion DM Maximum Strength Liquid & Robitussin Honey Adult Nighttime Cough DM Maximum Strength Liquid Value Pack (2-4 fl. 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